遗传学一览 Medical Genetics at a Glance
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作者： Dorian Pritchard 著
出 版 社： Oversea Publishing House
出版时间： 2002-12-1字数：版次： 1页数： 115印刷时间： 2002/12/01开本： 大16开印次： 1纸张： 胶版纸I S B N ： 9780632063727包装： 平装内容简介
Medical Genetics at a Glance is a concise, well-illustrated and accessible genetics textbook. It follows the now familiar, easy-to-use, double page spread format of the At a Glance series. Each double page presents clear, memorable diagrams that illustrate essential information with accompanying text that covers key topics and issues in more detail.
Structured into three distinct sections, Medical Genetics at a Glance takes the student through developmental biology, medical genetics and the clinical application of genetics. The first section focuses on basic biological concepts such as cell and chromosome structure, molecular biology and the cell cycle, as well as human embryonic development and sexual maturation. The second section applies these principles to medicine through the essential 'laws' of inheritance, the chromosome anomalies, multifactorial inheritance, normal polymorphism and gene frequency, then moving on to gene mapping, mutagenesis, cancer and immunogenetics. The final section addresses the clinical application of the above principles in pedigree drawing and molecular diagnostic procedures based on the human gene map, PCR and Southern techniques, risk assessment, genetic counselling, gene therapy and much more.
Medical Genetics at a Glance is an ideal resource that fits the budget and reading time of medical students and those seeking a quick, thorough introduction to this fast moving field. It can be used as primary or supplementary reading in a lecture-based course and is perfect for exam preparation.
目录
Preface
Acknowledgements
Part Ⅰ Developmental biology
1 Basic biology
2 The cell
3 The chromosomes
4 DNAstructure
5 DNAreplication
6 RNAstructure
7 Production of messenger RNA
8 Protein synthesis
9 The cell cycle
10 Gametogenesis
11 Embryology
12 Sexual differentiation
Part Ⅱ Medical genetics
13 The place of genetics in medicine
14 Chromosomal aneuploidies
15 Chromosome structural abnormalities
16 Mendel's laws
17 Autosomal dominant inheritance
18 Autosomalrecessiveinheritance
19 Intermediate inheritance
20 Sex-related inheritance
21 Congenital abnormalities
22 Multifactorial threshold traits
23 The common disorders of adult life
24 Twin studies
25 Normal polymorphism
26 Allele frequency
27 Genetic linkage and disease association
28 Gene mapping
29 Mutagenesis and DNA repair
30 Mutations
31 The molecular biology of cancer
32 Familial cancers
33 lmmunogenetics
Part Ⅲ Clinical applications of genetics
34 Clinical applications of genetics: an overview
35 Pedigree drawing
36 Risk assessment
37 Dysmorphology
38 Chromosome analysis
39 Biochemical diagnosis
40 Reproductive genetic counselling
41 Prenatal sampling
42 Linkage analysis
43 DNA sequencing
44 Southern blotting
45 The polymerase chain reaction
46 DNAprofiling
47 Avoidance and prevention of disease
48 The management of genetic disease
Glossary
Appendix: Information resources
Index
