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vander肾脏生理学 Vander's Renal Physiology

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作者: Douglas C. Eaton等著

出 版 社: Oversea Publishing House

出版时间: 2002-2-1字数:版次:页数: 214印刷时间: 2002/02/01开本: 32开印次:纸张: 胶版纸I S B N : 9780071357289包装: 平装内容简介

This concise overview of renal physiology introduces basic science principles and their relevance in the clinical expression of disease. Each chapter incorporates a wealth of pedagogical aids including: study questions, learning objectives, and clinical examples. Also serves as a good review for the USMLE Step 1.

作者简介:

Douglas C. Eaton, Ph.D.: Distinguished Professor, Department of Physiology; and Director, Center for Cell and Molecular Signaling, Emory University Medical School, Atlanta John Pooler, Ph.D.: Associate Professor of Physiology, Department of Physiology, Emory University Medical School, Atlanta .

目录

Preface

Chapter 1 Renal Functions,Snatomy,and Basic Processes

Functions

Anatomy of the Kidneys and Urinary System

The Nephron

Blood Supply to the Nephrons

Basic Renal Processes

Chapter 2 Renal Blood Flow and Glomerular Filtration

Glomerular Filtration and Renal Blood Flow

Flow, Resistance, and Pressure in The Kidneys

Glomerular Filtration

Autoregulation

Chapter 3 Clearance

Clearance Units

Plasma Creatinine and Urea Concentrations as Indicators of GFR Changes

Chapter 4 Basic Transport Mechanisms

Crossing the Epithelial Barriers

Receptor-Mediated Endocytosis and Transcytosis

Transport Mechanisms in Reabsorption

Chapter 5 Renal Handling of Organic Substances

Active Proximal Reabsorption of Organic Nutrients (Eg, Glucose, Amino Acids)

Proteins and Peptides

Active Proximal Secretion of Organic Anions

Active Proximal Secretion of Organic Cations

pH Dependence of Passive Reabsorption or Secretion Urea

Chapter 6 Basic Renal Processes for Sodiun,Chloride,and Water

Overview

Individual Tubular Segments

Urinary Concentration: The Medullary Osmotic Gradient

Chapter 7 Control of Sodium and Water Excretion:Regulation of Plasma Volume and Plasma Osmolality and Renal Control of Systemic Blood Pressure

Regulation of Blood Pressure

Contribution of The Kidney to The Long-Term Regulation of Blood Pressure

Control of Sodium Balance

Control of Water Excretion

Chapter 8 Renal Regulation of Potassium Balance

Regulation of Potassium Between the Intracellular and Extracellular Compartments

Renal Potassium Handling

Chapter 9 Regulation of Hydrogen Ion balance

Guidelines for Studying Acid-Base Biology

Renal Handling of Acids and Bases

Renal Excretion of Acid and Base

Hydrogen Ion Excretion on Urinary Buffers

Phosphate and Organic Acids as Buffers

Hydrogen Ion Excretion on Ammonium

Quantification of Renal Acid-Base Excretion

Regulation of the Renal Handling of Acids and Bases

Control of Renal Glutamine Metabolism and NH4 Excretion

Intravenous Solutions: Lactated Ringer's

Specific Categories of Acid-Base Disorders

Renal Response to Metabolic Acidosis and Alkalosis

Factors Causing the Kidneys to Generate or Maintain

A Metabolic Alkalosis

Chapter 10 Regulation of Calcium and phosphate Balance

Effector Sites for Calcium Balance

Hormonal Control of Effector Sites

Overview of Renal Phosphate Handling

Answers to Study Questions

Appendix A

Appendix B

Index

 
 
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