Apoptosis and Cancer Therapy: From Cutting-edge Science to Novel Therapeutic Concepts 2set

基本信息出版社:Wiley-VCH; 1 (2006年4月18日)精装:1159页正文语种:英语ISBN:3527312374条形码:9783527312375商品尺寸:17.5 x 6.8 x 24.6 cm商品重量:2.5 KgASIN:3527312374商品描述内容简介Here, an international and highly distinguished team of authors leads readers from the principles of programmed cell death to the role of apoptosis in cancer development and emerging treatment strategies. Divided into two distinct parts, the first focuses on apoptosis signaling, covering in depth such topics as mitochondria, effector systems, the Bcl-2 family, IAPs, survival pathways, tumor suppressor genes, modulators, lysosomes and phagocytosis. The second section goes on to analyze apoptosis in cancer and cancer therapy, with a detailed look at model systems, molecular diagnosis, cellular stress, DNA damage and repair, molecular targets and therapeutic aspects. With its strong focus on recent developments in cancer therapy, this book is aimed at oncologists, molecular and cell biologists, biochemists, and those working in the pharmaceutical and biotechnological industries.媒体推荐"...this excellent book on research in cell death is on the forefront of modern molecular oncology." (New England Journal of Medicine, December 21, 2006)